
Program for the Third International Rushmore Conference:
Strategies in the Prevention of Enteric Disease and Dissemination of Food-Borne Pathogens
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Thursday, September 29, 2005
4:00 - 6:00 pm Rushmore Conference Registration
Session I - Conference Opening Session and Social (Philip Hardwidge-presiding)
6:00 Welcome and Opening Remarks
6:15 Fatty Acid Inhibition of Microbial Adhesion of Cryptosporidium Parvum Sporozoites - Mark Kuhlenschmidt* and
Joann Schmidt, *University of Illinois
6:30 Pathogenesis of Colostridium difficile Infection in Piglets - M. Kevin Keel, J. Glenn Songer*, *University of Arizona
6:45 Polyclonal Antibody-Enriched Active Whey Powder Made of Bovine Milk, for the Prevention of Relapse in Clostridium
difficile-associated Diarrhea - Jaap T. van Dissel, Nanda de Groot*, Charles M. Hensgens, Sandra C. Numan,
Ed J. Kuijper, and Jan W. van 't Wout, *Mucovax bv, Leiden, The Netherlands
7:00 Induction of 'Peyer's Patch Independent' Immune Responses against E. coli F4 Fimbriae in the Small Intestine of Pigs - M.W. Salles*, M. Danabassis, R. Buchanan, J. Whale and V. Gerdts, *University of Saskatchewan
7:15 Epitope Mapping of Campylobacter jejuni NCTC 11168 FlaA Proteing Using Synthetic Peptides Probed with
Antibodies against Multiple C jejuni Serotypes - Ursla Fernando*, Debabrata Biswas, Brenda Allan, Sam Attah-
Poku and Andrew Potter, *University of Saskatchewan
7:30 Endocytosis of Escherichia coli STb Toxin in NIH-3T3 Cells - J. Daniel Dubreuil*, Stephanie M. A. Penel, Phuong
U. Le and Ivan-Robert Nabi, *Universite de Montreal
7:45 Siderophore Receptors and Porins as Vaccine Antigens Against Salmonellosis and E. Coli - James Sandstrom*,
Daryll Emery, Darren Straub, Doug Burkhardt, Larry Slinden and Laura Wonderling, *Eptiopix, Willmar, MN
8:00 Control of Pathogens Using Rumen Defaunation - Mark Rasmussen*, Sharon Franklin, Clayton McNeff and Steve
Carlson, *National Animal Disease Center, Ames, IA
8:15 LEE-encoded Regulator (Ler) Mutants Elicit Serotype-specific Protection, but not Cross-protection, against Attaching
and Effacing E. coli Strains - Chengru Zhu, C., Shouzang Feng, Zhoulou Yang, Katherine Davis, Hernan Rios,
James Kaper and Edgar Boedeker*, *University of Maryland Baltimore
8:30 Refreshments and Cash Bar
Friday, September 30, 2005
Session II - Development of Models for Pathogenesis and Protection Studies (Richard Isaacson)
8:00 Salmonella Takes its Toll on the Host - Andreas Baumler, University of California, Davis
8:45 Enterohemorrhagic E. coli - Tom Besser, Washington State University
9:30 Use of Germ-free Pigs in Modeling Entertoxigenic E. coli Infections - David Francis*, Alan Erickson, Rodney
Moxley, Weiping Zhang and Emil Berberov, *Center for Infectious Disease Research and Vaccinology, South
Dakota State University
10:15 Break
10:35 Vaccines to Induce Protective Mucosal Immunity to Rotavirus Evaluated in a Neonatal Gnotobiotic Pig Disease Model - L.J. Saif*, L. Yuan, M. Azevedo, A. Gonzalez, T.V. Nguyen, *The Ohio State University
11:20 Natural and Experimental Prion Diseases of Cattle - Juergen A. Richt*, Amir N. Hamir, Robert A. Kunkle, Eric M.
Nicholson, Justin J. Greenlee, Janice M. Miller, Randall Cutlip, Arthur J. Davis, S. Mark Hall, *National Animal
Disease Center, Ames, IA
12:05 Lunch - Catered
Session III - Strategies for the Development of Enteric Vaccines (Alan Young)
1:00 Role of Commensal Bacteria in Development of GALT and the Immune System - Katherine Knight, Loyola University
1:45 Transcutaneous Immunization against ETEC - Sarah A. Frech, Iomai Corporation, Gaithersburg, MD
2:30 DNA Vaccines and CpG Adjuvants and Immunostimulants - George Mutwiri, (VIDO), University of Saskatchewan
3:15 Break
3:30 Recombinant Attenuated Salmonella Vaccines to Enhance Food Safety and Provide an Economic Benefit to Poultry
Producers - Roy Curtiss III, The Biodesign Institute at Arizona State University
4:15 Use of Live Lactococci as Safe Mucosal Vaccine - Luis G. Bermudez-Humaran, Naima G. Cortes-Perez,
Francois Lefevre, Valeria Guimaraes, Juan M. Alcocer-Gonzales, Alexandra Gruss, Gerard Corthier and
Philippe Langella*, *Unite d'Ecologie et de Physiologie du Systeme Digestif, INRA, Jouy-En-Josas, France
5:00 Session Closes
5:30 Evening visit and dinner at the Mt. Rushmore National Memorial
**After Dinner Presentation: Wildlife of the Black Hills - Jonathan Jenks, Department of Wildlife and Fisheries
Sciences, South Dakota State University
Saturday, October 1, 2005
Session IV - Advances in Vaccine Development (Connie Gebhart)
8:00 Vaccination against Type III Secreted Proteins as a Strategy to Control Escherichia coli O157:H7 in Cattle - Rodney
A. Moxley, University of Nebraska
8:45 Update on Vaccines against Typhoid Fever - Myron M. Levine, University of Maryland School of Medicine
9:30 Advances in the Understanding of Campylobacter jejuni Virulence Determinants - Michael E. Konkel*, Preeti Malik-
Kale, Craig T. Parker, Lynn A. Joens, Sophia Pacheco and Jeffery Christensen, *School of Molecular
Biosciences, Washington State University
10:15 Break
10:35 Oral Immunization of Piglets with Fimbrial Antigens (F4/K88) against Enterotoxigenic Escherichia coli (post-weaning
diarrhea) - Bruno Goddeeris*, Frank Verdonck, Veerle Snoeck, Wim Van den Broeck and Eric Cox, *University
of Ghent, Belgium
11:20 Plant-made Vaccines - Their Development and Maturation - Amanda M. Walmsley*, Dwayne D. Kirk, Chuck
Mihaliak, Steve R. Webb, *The Biodesign Institute at Arizona State University
12:05 Lunch Break
Session V - Alternative Strategies for the Control of Enteric Diseases and Food-borne Pathogens (Lynn Joens)
2:00 Novel Strategies for the Control of Food-borne Pathogens in Livestock and Poultry - David J. Nisbet, Food and Feed
Safety Research Unit, ARS, USDA, College Station, TX
2:45 Recombinant Antimicrobial Proteins, Lactoferrin and Lysozyme, Produced in Plants for Control of Enteric Pathogens -
Ning Huang, Ventria Bioscience, Sacramento, CA
3:30 Break
3:50 Development of Passive Immunotherapy Technology for the Control of Infectious Disease - T. Sathiyaseelan,
Hematech, Sioux Falls, SD
4:35 Session Closes
Session VI - Poster Presentations/Closing Social/Cash Bar
7:00-9:00
Sunday, October 2, 2005
8:15-3:30 Optional Tour of Black Hills Attractions
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Center for Infectious Disease Research and Vaccinology
South Dakota State University
Box 2175
Brookings, SD USA 57007