Conference Program

Program for the Third International Rushmore Conference:

Strategies in the Prevention of Enteric Disease and Dissemination of Food-Borne Pathogens

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Thursday, September 29, 2005

    4:00 - 6:00 pm  Rushmore Conference Registration

 

Session I - Conference Opening Session and Social (Philip Hardwidge-presiding)

 

    6:00    Welcome and Opening Remarks

    6:15    Fatty Acid Inhibition of Microbial Adhesion of Cryptosporidium Parvum Sporozoites - Mark Kuhlenschmidt* and 

              Joann Schmidt, *University of Illinois

    6:30    Pathogenesis of Colostridium difficile Infection in Piglets - M. Kevin Keel, J. Glenn Songer*, *University of Arizona

    6:45    Polyclonal Antibody-Enriched Active Whey Powder Made of Bovine Milk, for the Prevention of Relapse in Clostridium 

              difficile-associated Diarrhea - Jaap T. van Dissel, Nanda de Groot*, Charles M. Hensgens, Sandra C. Numan, 

              Ed J. Kuijper, and Jan W. van 't Wout, *Mucovax bv, Leiden, The Netherlands

    7:00    Induction of 'Peyer's Patch Independent' Immune Responses against E. coli F4 Fimbriae in the Small Intestine of Pigs -              M.W. Salles*, M. Danabassis, R. Buchanan, J. Whale and V. Gerdts, *University of Saskatchewan

    7:15    Epitope Mapping of Campylobacter jejuni NCTC 11168 FlaA Proteing Using Synthetic Peptides Probed with 

              Antibodies against Multiple C jejuni Serotypes - Ursla Fernando*, Debabrata Biswas, Brenda Allan, Sam Attah-

              Poku and Andrew Potter, *University of Saskatchewan

    7:30    Endocytosis of Escherichia coli STb Toxin in NIH-3T3 Cells - J. Daniel Dubreuil*, Stephanie M. A. Penel, Phuong 

              U. Le and Ivan-Robert Nabi, *Universite de Montreal

    7:45    Siderophore Receptors and Porins as Vaccine Antigens Against Salmonellosis and E. Coli - James Sandstrom*, 

              Daryll Emery, Darren Straub, Doug Burkhardt, Larry Slinden and Laura Wonderling, *Eptiopix, Willmar, MN

    8:00    Control of Pathogens Using Rumen Defaunation - Mark Rasmussen*, Sharon Franklin, Clayton McNeff and Steve 

              Carlson, *National Animal Disease Center, Ames, IA

    8:15    LEE-encoded Regulator (Ler) Mutants Elicit Serotype-specific Protection, but not Cross-protection, against Attaching 

              and Effacing E. coli Strains - Chengru Zhu, C., Shouzang Feng, Zhoulou Yang, Katherine Davis, Hernan Rios, 

              James Kaper and Edgar Boedeker*, *University of Maryland Baltimore

    8:30    Refreshments and Cash Bar

         

Friday, September 30, 2005   

Session II - Development of Models for Pathogenesis and Protection Studies (Richard Isaacson)

    

    8:00    Salmonella Takes its Toll on the Host - Andreas Baumler, University of California, Davis

    8:45    Enterohemorrhagic E. coli - Tom Besser, Washington State University

    9:30    Use of Germ-free Pigs in Modeling Entertoxigenic E. coli Infections - David Francis*, Alan Erickson, Rodney 

              Moxley, Weiping Zhang and Emil Berberov, *Center for Infectious Disease Research and Vaccinology, South 

              Dakota State University

  10:15    Break

  10:35    Vaccines to Induce Protective Mucosal Immunity to Rotavirus Evaluated in a Neonatal Gnotobiotic Pig Disease Model -              L.J. Saif*, L. Yuan, M. Azevedo, A. Gonzalez, T.V. Nguyen, *The Ohio State University

  11:20    Natural and Experimental Prion Diseases of Cattle - Juergen A. Richt*, Amir N. Hamir, Robert A. Kunkle, Eric M. 

              Nicholson, Justin J. Greenlee, Janice M. Miller, Randall Cutlip, Arthur J. Davis, S. Mark Hall, *National Animal 

              Disease Center, Ames, IA

  12:05    Lunch - Catered

 

 

Session III - Strategies for the Development of Enteric Vaccines (Alan Young)

    

    1:00    Role of Commensal Bacteria in Development of GALT and the Immune System - Katherine Knight, Loyola University

    1:45    Transcutaneous Immunization against ETEC - Sarah A. Frech, Iomai Corporation, Gaithersburg, MD

    2:30    DNA Vaccines and CpG Adjuvants and Immunostimulants - George Mutwiri, (VIDO), University of Saskatchewan

    3:15    Break

    3:30    Recombinant Attenuated Salmonella Vaccines to Enhance Food Safety and Provide an Economic Benefit to Poultry 

              Producers - Roy Curtiss III, The Biodesign Institute at Arizona State University

    4:15    Use of Live Lactococci as Safe Mucosal Vaccine - Luis G. Bermudez-Humaran, Naima G. Cortes-Perez, 

              Francois Lefevre, Valeria Guimaraes, Juan M. Alcocer-Gonzales, Alexandra Gruss, Gerard Corthier and 

              Philippe Langella*, *Unite d'Ecologie et de Physiologie du Systeme Digestif, INRA, Jouy-En-Josas, France

    5:00    Session Closes

    5:30    Evening visit and dinner at the Mt. Rushmore National Memorial

              **After Dinner Presentation: Wildlife of the Black Hills - Jonathan Jenks, Department of Wildlife and Fisheries 

              Sciences, South Dakota State University

 

Saturday, October 1, 2005   

Session IV - Advances in Vaccine Development (Connie Gebhart)

    

    8:00    Vaccination against Type III Secreted Proteins as a Strategy to Control Escherichia coli O157:H7 in Cattle - Rodney 

              A. Moxley, University of Nebraska 

    8:45    Update on Vaccines against Typhoid Fever - Myron M. Levine, University of Maryland School of Medicine

    9:30    Advances in the Understanding of Campylobacter jejuni Virulence Determinants - Michael E. Konkel*, Preeti Malik-

              Kale, Craig T. Parker, Lynn A. Joens, Sophia Pacheco and Jeffery Christensen, *School of Molecular 

              Biosciences, Washington State University

  10:15    Break

  10:35    Oral Immunization of Piglets with Fimbrial Antigens (F4/K88) against Enterotoxigenic Escherichia coli (post-weaning 

              diarrhea) - Bruno Goddeeris*, Frank Verdonck, Veerle Snoeck, Wim Van den Broeck and Eric Cox, *University 

              of Ghent, Belgium

  11:20    Plant-made Vaccines - Their Development and Maturation - Amanda M. Walmsley*, Dwayne D. Kirk, Chuck 

              Mihaliak, Steve R. Webb, *The Biodesign Institute at Arizona State University

  12:05    Lunch Break

 

 

Session V - Alternative Strategies for the Control of Enteric Diseases and Food-borne Pathogens (Lynn Joens)

    

    2:00    Novel Strategies for the Control of Food-borne Pathogens in Livestock and Poultry - David J. Nisbet, Food and Feed 

              Safety Research Unit, ARS, USDA, College Station, TX

    2:45    Recombinant Antimicrobial Proteins, Lactoferrin and Lysozyme, Produced in Plants for Control of Enteric Pathogens - 

              Ning Huang, Ventria Bioscience, Sacramento, CA

    3:30    Break

    3:50    Development of Passive Immunotherapy Technology for the Control of Infectious Disease - T. Sathiyaseelan

              Hematech, Sioux Falls, SD

    4:35    Session Closes

 

Session VI - Poster Presentations/Closing Social/Cash Bar

    

    7:00-9:00

 

Sunday, October 2, 2005   

    8:15-3:30    Optional Tour of Black Hills Attractions

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Center for Infectious Disease Research and Vaccinology

South Dakota State University

Box 2175

Brookings, SD USA  57007